For more than 25 years, biologist David Goodsell has been making scientifically accurate paintings and illustrations of the molecular structures of things related to HIV, cancer cells, ebola, Zika, diabetes, proteins, enzymes, and hundreds of other scientific and medical processes.
Since the early 1990s, I have been working with a type of illustration that shows portions of living cells magnified so that you can see individual molecules. I try to make these illustrations as accurate as possible, using information from atomic structure analysis, electron microscopy, and biochemical analysis to get the proper number of molecules, in the proper place, and with the proper size and shape.
Much of his work is available to use for free (with attribution) and is scattered across the web: the Molecule of the Month, Molecular Landscapes, Illustrations for Public Use. He has also published several books of his paintings, the most popular of which is The Machinery of Life. Science magazine recently profiled Goodsell and his work.
In addition to studying pictures of cells from high-powered microscopes, Goodsell relies on molecular structures from electron microscopy (EM), x-ray crystallography, and nuclear magnetic resonance spectroscopy to make his paintings, which show the often crowded and complex world of cells and the microbes that infect them. He even uses the known weights of molecules if that’s all he has so that he can at least draw, say, a correctly sized circle. “I’m a scientist first,” he says. “I’m not making editorial images that are meant to sell magazines. I want to somehow inform the scientists and armchair scientists what the state of knowledge is now and hopefully give them an intuitive sense of how these things really look — or may look,” he says.
May look?
“These pictures have tons and tons and tons of artistic license,” he says. “They’re just one snapshot of something that’s intrinsically superdynamic. Every time I do a painting, the next day it’s out of date because there’s so much more data coming out.”
Here’s a quick video profile as well:
All images are by David S. Goodsell, the Scripps Research Institute. (via alexandra kammen)
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